二甲双胍对糖尿病患者血脂的影响分析

The Blood Lipid Analysis of Metformin for Diabetes

目的:探讨二甲双胍对糖尿病患者血脂的影响。方法:初发2型糖尿病患者160例平分为两组-治疗组与对照组。对照组单独应用格列齐特缓释片治疗,治疗组应用二甲双胍及格列齐特缓释片治疗。结果:治疗组血糖达标时间为(13.6±1.2)天,对照组血糖达标时间为(17.8±2.1)天,治疗组达标时间明显少于对照组,但是两组相比无显著性差异(P>0.05)。治疗前两组TG、TC、LDL-C无明显差异(P>0.05);治疗后,两组的胆固醇(TG)、甘油三酯(TC)低密度脂蛋白胆固醇(LDL)较治疗前显著下降(P<0.05)。不过治疗组中的下降程度都明显高于对照组(P<0.05)。结论:二甲双胍应用于糖尿病的治疗可加快血糖达标时间,同时减轻体重,有利于血脂代谢的恢复,值得推广应用[11]。

Objective：To investigate the blood lipid analysis of metformin for diabetes.Methods：The onset of type 2 diabetes 160 cases were equally divided into two groups-treatment and control groups.The control group uses gliclazide MR treatment,and the treatment group used the metformin and gliclazide MR treatment.Results：The time of blood glucose（13.6±1.2） days in the treatment group,so that was（17.8 ± 2.1） days in the control group,the two groups showed no significant difference（P〈0.05）.Before treatment,the level of TG,TC,LDL-C hadno significant difference（P〈0.05）;after treatment,both groups of cholesterol（TG）,triglycerides（TC） low-density lipoprotein cholesterol（LDL） decreased significantly compared with before treatment（P〈0.05）.However,the decline in the extent of the treatment group were significantly higher（P〈0.05）.Conclusion：Metformin used in the treatment of diabetes,can speed up the time of blood glucose and lose weight,it is conducive to the recovery of lipid metabolism,should be widely applied.