尿液培养病原菌的分布及耐药性分析

Urine Culture of the Pathogen Distribution and Drug Resistance Analysis

目的对泌尿系感染病原菌的分布及其耐药性等情况进行分析与探讨,为临床合理的应用抗生素提供重要的依据。方法对本医院自2009年3月～2011年10月之间住院及门诊患者尿培养阳性319例细菌资料进行回顾性总结与分析。结果 12例尿液细菌培养分离出172株细菌分布,其中细菌类型主要有大肠埃希菌、肠球菌,分别占到48.9%,肠球菌占14.2%。肠球菌属对环丙沙星、利福平、庆大霉素具有较高的耐药率,达到60%以上,大肠埃希菌的耐药性则主要体现在哌拉西林、环丙沙星、氧氟沙星上。对头孢类具有敏感性,但不太明显。结论在临床治疗过程中应该根据尿液培养病原菌的分布以及耐药性变化,合理的选择和科学的使用抗生素,以保证更加有效地遏制耐药菌的生长。

Objective To urinary tract infection of the pathogen and its resistance distribution status analysis and studies,reasonable use of antibiotics for clinical provide important basis. Methods This hospital from March 2009 to October 2011 in hospital and clinic patients between urine culture positive data were analyzed 319 cases of bacteria were retrospectively summarized and analyzed. Results 12 cases of urine training 172 strains of bacteria isolated bacteria distribution,including bacteria types have mainly escherichia coil,ira coccus,respectively to 48.9%,the bowel coccus accounted for 14.2%Coccus of bowel to ciprofloxacin,rifabutin,gentamicin is of high rate of higher, achieve 60% above,escherichia coli strains of the mainly reflects in piperacillin,ciprofloxacin,levofloxacin.Which is sensitive to cephalosporins,but not too obvious, Conclusion In the clinical treatment process should be according to the urine culture of the pathogen distribution and drug resistance changes, the choice of reasonable and scientific use of antibiotics,to ensure that more effective way to curb the growth of antibiotic resistant bacteria.