小儿复杂型热性惊厥临床研究

Clinical research of complex febeile convulsion in children

目的研究小儿复杂型热性惊厥的临床特征。方法将2006年2月至2010年6月商丘市第一人民医院收治热性惊厥惠儿168例分为单纯型热性惊厥组130例和复杂型热性惊厥组38例。观察临床特征、围产史、家族惊厥史、惊厥发生时体温、发作时间、发作次数、血清钠、血清钙、脑电图检查等，并进行比较。结果168例热性惊厥中患儿单纯型热性惊厥130例，占77．38％，复杂型热性惊厥38例，占29．23％。对本研究患儿进行跟踪随访1—4年，复杂型热性惊厥38例中发展为癫痫9例，癫痫发生率为23．68％；单纯型热性惊厥130例发展为癫痫4例，癫痫发生率为3．07％。结论复杂型热性惊厥具有惊厥发生时月龄较大，有家族惊厥史、围产史等异常高危因素，惊厥发生时体温相应较低，发作持续时间长和发作次数较多特点。复杂型热性惊厥转化成癫痫几率高，应高度重视，积极控制防止和避免再发作。

Objective To study the clinical features of complex febeile convulsion in children. Methods Totally 168 patients with febeile convulsion from February 2006 to June 2010 in the first peo- ple＇ s hospital of Shangqiu were divided into two groups, simple febrile seizure （SFS） group with 130 ca- ses and complex febeile convulsion （CFS） group with 38 cases. The perinatal history, family history of seizures, body temperature when convulsions occurs, frequency, time, serum sodium, serum calcium and encephlogram were observed and compared. Results Patients with SFS were 130 cases, accounting for 77.38% , and patients with CFS were 38 cases, accounting for 29.23%. Patients were followed-up for 1 -4 years,9 cases（23.68% ） developed to epilepsy in CFS group. Four cases（3.07% ） developed to epilepsy in SFS group. Conclusions Patients with CFS have high risk factors as the moon＇ s age, family history of seizures, abnormal perinatal history. The temperature is low when seizures occures, with long time and high frequency. The incidence of CFS develop to epilepsy is high, so we should prevent and a- void the development.