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不同剂量咪唑安定预防腹腔镜胆囊切除术患者术中知晓的效果 被引量:1

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摘要 目的观察不同剂量咪唑安定预防全身麻醉腹腔镜胆囊切除术(LC)患者术中知晓的效果及对苏醒质量的影响。方法选择120例择期在全身麻醉下行LC患者,随机分为A、B、C三组,每组40例,诱导时分别静脉注射咪唑安定0.02、0.05、0.1mg/kg,其余用药三组相同,观察术中知晓情况和术后清醒时间、拔管时间及拔管后警觉/镇静(OAA/S)评分。结果A组术中知晓病例显著多于B组和C组(P〈0.05),B组和C组间比较差异无统计学意义(P〉0.05);C组术后清醒时间和拔管时间明显长于A组和B组(P〈0.01),C组拔管后OAA/S评分高于A组和B组(P〈0.01),A组和B组间比较差异无统计学意义(P〉0.05)。结论全身麻醉诱导时应用0.05mg/kg咪唑安定能有效预防Lc患者术中知晓的发生,苏醒平稳质量较高。
出处 《中国实用医刊》 2012年第18期69-70,共2页 Chinese Journal of Practical Medicine
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