中西医结合治疗垂体泌乳素微腺瘤疗效分析

Efficacy Analysis of Integrative Medicine Treatment for Prolactin-secreting Pituitary Microadenoma

目的:通过对中医联合溴隐亭和单纯溴隐亭治疗垂体泌乳素微腺瘤的效果比较,探讨规范、更有效的垂体泌乳素微腺瘤的药物治疗方法。方法:将入选的50例垂体泌乳素微腺瘤女性患者随机分成两组,每组25例。两组病人分别接受中药加溴隐亭和单纯溴隐亭治疗。比较两种治疗方法在降低催乳素水平、治愈率、有效率和不良反应发生率等方面的差异,并做相应的统计学处理。结果:两组治疗后催乳素水平在治疗后3个月有显著差异,在6个月和9个月均无显著差异;两组治疗前后的催乳素水平均有显著差异;两组的治愈率有显著差异,有效率无显著差异。结论:中西医结合与单纯西药对降低血泌乳素水平均有效,中西医结合在改善月经及促进怀孕方面较单纯应用溴隐亭效果更好。

Objective：To explore normative,more effective medication for pituitary prolactinoma via the comparision of Traditional Chinese medicine combined with Bromocriptine and single Bromocriptine treating the pituitary prolactinoma.Methods：50 selected female patients with prolactinoma were divided into two groups,25 patients in each group.The two groups accepted the treatment of Traditional Chinese medicine combined Bromocriptine respectively,and the decrease of the prolactin levels,curative rate,effective rate and incidence of side effectives were analyzed statistically.Results：The prolactin levels of the two groups were significantly different 3 months after treatment,not significantly different 6 months or 9 months after treatment.The prolactin levels of the groups were significantly different before and after treatment respectively.The curative rate was significantly different,and the effective rate was not significantly different.Conclusion：Traditional Chinese medicine combined with Bromocriptine and single Bromocriptine are effective on decreasing prolactin level.Traditional Chinese medicine combined Bromocriptin is more effective in meliorating menses and asisting pregnancy than single Bromocriptin.