胰岛素泵在2型糖尿病治疗中的应用

Clinical observation of insulin pump therapy in type 2 diabetes

目的探讨应用两种不同胰岛素给药方式治疗2型糖尿病的临床效果。方法选取2型糖尿病患者118例，数字表法随机分为胰岛素泵组（CsⅡ组）59例和皮下注射胰岛素组（MDⅡ组）59例，分别采用胰岛素泵和皮下注射给药方式治疗，观察其治疗效果。结果两组患者经治疗后血糖均明显下降，CSII组控制血糖达标时间（4．5±1．3）d，短于MDII组的（7．2±2．3）d，胰岛素用量显著减少，低血糖发生率低（均P〈0．05）。结论胰岛素泵给药治疗2型糖尿病较皮下注射胰岛素更安全有效，且无明显不良反应。

Objective To explore the clinical effect of the two different administration style of insulin pump to treat type 2 diabetes. Methods 118 patients with type 2 diabetes were selected and randomly divided into the experimental group, which 59 cases of the patients were treated with insulin pump （ CSII group ） and the control group,which 59 cases of the patients with subcutaneous injecting of insulin. The treat ment effects were observed. Results The blood glucose level of the two groups of patients was significantly decreased after treatment, the CSII group spend shorter time [ （4.5 ± 1.3 ） d vs （7.2 ± 2.3 ） d ], used a significantly less dose of insulin and has a lower incidence of hypoglycemia than the MDII group in the course of decreasing the blood glucose to aimed level（ all P 〈 0. 05）. Conclusion Insulin pump is safe and more effective than subcutaneous injecting insulin in treating type 2 diabetes, and has no significant adverse reactions, worthy of clinical application.