我院住院患者抗菌药物不合理使用分析

Analysis on irrational use of antimicrobial drugs of inpatients in our hospital

目的:调查住院患者抗菌药物的使用情况,为进一步规范抗菌药物的使用提供参考。方法:从我院2011年7月使用抗菌药物的住院病历中随机抽取414份,对抗菌药物的用法用量、药物选择及Ⅰ类切口手术预防性使用等情况进行统计分析。结果:414份病历中,抗菌药物不合理使用率为20.5%;头孢西丁不合理使用频次最高,占23.2%;最常见的不合理用药表现为用药剂量过大,占48.2%;此外,Ⅰ类切口手术预防性用药持续时间过长,多数超过24 h,少数甚至达到1周左右。结论:我院抗菌药物的使用尚存在不合理之处,应加强对医护人员的知识培训、加强管理力度,以促进抗菌药物的合理使用。

Objective： To investigate the use of antimicrobial drugs of inpatients and analyze the main irrational manifestations, in order to provide reference for normative and rational administration of antimicrobial drugs. Methods： A total of 414 cases of inpatients who used the antimicrobial drugs in July 2011 were randomly selected from our hospital, the usage, dosage and choices of antimicrobial drugs and use of prophylactic antimicrobial agents in patients with type I incision operation were analyzed statistically. Results： The rate of irrational use of antimicrobial drugs was 20.5% in 414 cases. The frequency of irrational use of cefoxitin was the highest, accounting for 23.2%. The most common manifestation of irrational drug use was overdose of antimicrobial drugs, accounting for 48.2%. The treatment duration of prophylactic antimicrobials in type I incision operation was too long, in most cases the duration was more than 24 hours, and in a minority of cases the treatment course even reached 1 week or so. Conclusion： There were some irrational problems in use of antimicrobial drugs in our hospital, the improvement measures should include the strengthening of medical staff training and management in order to promote the rational use of antimicrobial drugs.