传染性腺胃炎组织病理学和超微结构的研究

STUDIES ON HISTOPATHOLOGY AND ULTRASTRUCTURE OF TRANSMISSIBLE PROVENTRICULITIS

近两年来 ,我国的许多地区流行了一种以腺胃肿胀 ,生长严重受阻为特征的传染病 传染性腺胃炎。对肿胀的腺胃组织进行组织学和超微结构的观察表明 ,腺上皮细胞以网状细胞组织增生为主 ,肿胀的细胞内有大量的空泡样结构 ,与马立克氏病、淋巴细胞白血病有明显的区别。从腺胃组织的超薄切片中可观察到 4种病毒颗粒 ,其中有 3种业已证明分别为网状内皮组织增生症病毒、冠状病毒和新城疫病毒 ,另一种病毒呈球形 ,大小在 6 0～ 80nm ,主要分布于细胞间隙中。

In the recent two years,a chicken infectious diseasetransmissible proventriculitis (TP) characterized with serious proventricular enlargement and stunted growth has occurred epidemically in many provinces of China.The histopathological and ultrastructural lesions in proventriculus,bursa of Febrcius,thymus,duodenum and kidney were studied.The typical lesions were necrosis of parrenchymal cells and the proliferation of reticular cells in various tissues.The ultrastructural characteristics of the proliferated proventricular gland (alveolar) epithelial cells were that with numerous processes in plasma membrane,which were distinguished from the morphological heterogeneous populations of lymphoid cells in Marek′s disease and the uniform lymphoblasts in lymphoid leukousis.Four strains of the viruses were found in proventricular tissues,three of them were recognized as reticuloendotheliosis virus,coronavirus and Newcastle disease virus.The another viruses were spherical shape,ranging from 60nm to 80nm in diameter,and could be found noly among cells.