幽门螺旋杆菌与冠心病相关性研究

Study on the relevance of helicobacter pylori and coronary heart disease

目的:研究冠心病与非冠心病患者幽门螺旋杆菌感染阳性率,同时分析幽门螺旋杆菌与冠心病发生的影响。方法:选择住院冠心病人88例为研究组,同期入院的其他心血管疾病患者56例为对照组。两组分别行14C尿素呼气试验、胆固醇、甘油三酯检查,比较两组幽门螺旋杆菌感染阳性率及胆固醇、甘油三酯的结果。结果:冠心病人组幽门螺旋杆菌感染阳性率比非冠心病人组高,幽门螺旋杆菌感染阳性患者比阴性患者胆固醇、甘油三酯更明显异常。结论:幽门螺旋杆菌感染可能是冠心病发生的一种独立危险因素,可影响脂质代谢异常。推断对幽门螺旋杆菌感染阳性的冠心病患者进行抗幽门螺旋杆菌治疗,可降低心血管事件的发生风险。

Objective：To study the positive rate of helicobacter pylori in coronary heart disease （CHD） and non - CHD patients and the effects of helicobacter pylori and CHD. Methods：88 CHD patients were chosen as research object group with 56 other patients as reference group. We have carried out the 14 C-urea breath, cholesterol and triglyceride tests, and compared the results of positive rate of helicobacter pylori, cholesterol and triglyceride in the two groups. Results：The positive rate of helicobacter pylori in CHD patients was higher than other patients, and with anomalous results in cholesterol and triglyceride tests. Conclusion： Those results suggested that the infection of helicobacter pylori, which can affect the metabolic abnormality of lipid, might be one of independent risk factors to CHD. The treatment of anti helicobacter pylori in the CHD patients may reduce the risk of cardiovascular diseases.