降纤酶治疗急性脑梗死的临床观察

Clinical Observation on Defibrase in the Treatment of Acute Cerebral Infarction

目的 观察降纤酶治疗急性脑梗死的疗效和安全性。 方法 治疗组 36例以降纤酶加常规药物治疗 ,对照组 36例同期以常规药物治疗 ,观察临床疗效及副作用。 结果 降纤酶治疗组治疗后 7天、 1 4天及 2 1天疗效均明显优于对照组 ;发病时间越短 ,疗效越明显 ;降纤酶组血浆纤维蛋白原明显下降 ;无明显出血现象及肝肾功能异常。 结论 降纤酶是治疗急性脑梗死疗效确切。

Objective To observe efficacy and safety of defibrase in the treatment of acute cerebral infarctionMethods 36 patients (defibrase group) with acute cerebral infarction was treated by defibrase and commonused drugs, 36 patients (control group) was treated by the commonused drugs at the same period Curative effcets and sideeffects of defibrase were estimated and observed Results The efficacy of defibrase group was significantly higher than that of control group after the treating on the 7th, 14th and 21st day The shorter ischemia appeared, the better curatrve effects were The plasma fibrinogen decreased obviously, no bleeding and clear sideeffects were found Conclusion Defibrase can be a safe and effective drug in the treatment of acute cerebral infarction