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女性高催乳素血症60例临床分析 被引量:3

Clinical Analysis of 60 Cases of Women with Hyperprolactinemia
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摘要 目的:探讨高催乳素血症(Hyperprolactinemia,HPRL)患者的发病原因、临床特点及其治疗原则。方法:选择妇科门诊高催乳素患者60例,根据实验室及辅助检查,明确发病原因,针对病因用溴隐亭治疗或手术治疗。结果:HPRL患者60例中垂体催乳素瘤占18.3%,甲低占16.6%,药物因素占8.3%,无明确病因占55%。结论:HPRL可引起月经量减少、闭经、溢乳、不孕及早期流产等临床症状,以药物治疗为主,同时针对病因可行手术及放疗治疗。 Objective: To explore the etiology,clinical characteristic,diagnosis and therapy of the patients with hyperprolactinemia.Methods: 60 cases of HPRL patients in the gynecology clinic of our hospital were studied.The pathogeny was confirmed by means of the experiments in the laboratory and the assistant examinations.Either bromoeriptin or operation could be adopted accordingly.Results: The pathogeny of 60 HPRL patients were prolactinema in proportion to 18.3%,hypothyroidism(16.6%),drugs(8.3%) and unknown causes(55%).Conclusion: The symptoms of HPRL patients are spanomenorrhea,amenorrhea,infertility and early abortion etc.Prolactinema patients can be treated with drugs mainly,and sometimes with surgical operation and radiotheropy according to their pathogeny.
作者 李艳 谢玉翠
出处 《山西职工医学院学报》 CAS 2012年第4期4-6,共3页 Journal of Shanxi Medical College for Continuing Education
关键词 高催乳素血症 垂体腺瘤 不孕症 溴隐亭 hyperprolactinemia prolactinema infertility bromoeriptin
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参考文献7

  • 1Andrews ZB, Grattan DR. Opioid Receptor Subtypes Involved in the Regulation of Prolactin Secretion during Pregnancy and Lactation [ J ]. Journal of Neuroendocrinology, 2003,15 ( 3 ) :227-236.
  • 2杨卉,林其德.高催乳素血症的研究进展[J].国外医学(计划生育分册),2004,23(3):147-150. 被引量:22
  • 3(美)LeonSperoff,(美)RobertH.Class,(美)NathanG.Kase.李继俊主译.临床妇科内分泌学与不孕[M].6版.济南:山东科学技术出版社,2003.
  • 4Senti O, Chik CL, Ur E, et al. Diagnosis and Management of Hyper- prolactinemia[J]. Canadian Medical Association, 2003,169 ( 6 ) : 575-581.
  • 5Emiliano AB, Fudge JL. From Galaetorrhea to Osteopenia. Rethin- king Serotonin-Prolactin Interactions [ J ]. Neuropsychopharmaeology, 2004, 29(5) :833-846.
  • 6Gudek A, Nat A, Gedik O. Isolated Adrenocorticotropie Hormone Deficiency, Thyroid Autoimmunity and Transient Hyperprolactinemia [J]. Endocr Pratt,2001,7(2) :102-105.
  • 7Valdemarsson S. Macroprolactinemia. Risk of Misdiagnosis and Mis- management in Hyperprolaetinemia [ J]. Lakartidningen, 2004, 101 (6) :458-465.

二级参考文献20

  • 1Biller BM, Luciano A, Crosignani PG,et al. Guidelines for the diagnosis and treatment of hyperprolactinemia. J Reprod Med, 1999, 44[12 Suppl]:1075-1084.
  • 2Andrews ZB, Grattan DR. Opioid receptor subtypes involved in the regulation of prolactin secretion during pregnancy and lactation. J Neuroendocrinol, 2003, 15(3):227-236.
  • 3Phelps JY, Bugg EM, Shamblott MJ, et al. Prolaction gene expression in human ovarian follicular cells. Fertil Steril, 2003, 79(1):182-185.
  • 4Vera-Lastra O, Luis J, Luis R, et al. Prolactin and autoimmun. Autoimmun Rev, 2002, 1:360-364.
  • 5Serri O, Chik CL, Ur E, et al, Diagnosis and management of hyperprolactinemia. CMAJ, 2003, 169(6):575-581.
  • 6Emiliano AB, Fudge JL, From galactorrhea to osteopenia: rethinking serotonin-prolactin interactions. Neuropsychopharmacology, 2004, 29(5):833-846.
  • 7Gurlek A, Nar A, Gedik O. Isolated adrenocorticotropic hormone deficiency, thyroid autoimmunity, and transient hyperprolactinemia. Endocr Pract, 2001, 7(2):102-105.
  • 8Inoue A, Seto M, Sugita S, et al, Differential effects on D2 doparnine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat pituitary. Brain Res Mol Brain Res, 1998, 55(2):285-289.
  • 9Valdemarsson S. Macroprolactinemia: Risk of misdiagnosis and mismanagement in hyperprolactinemia. Lakartidningen, 2004, 101 (6):458-465.
  • 10Vallette-Kasic S, Morange-Ramos I, Selim A, et al. Macroprolactinemia revisited: a study on 106 patients. J Clin Endocrinol Metab, 2002,87:581-588.

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