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HCG注射日血清孕激素水平对IVF长方案继续妊娠率的影响 被引量:4

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摘要 目的探讨体外受精胚胎移植(IVF/ICSI-ET)超促排卵中,HCG注射日血清孕酮(P)微量升高对妊娠结局的影响,并探索其最佳界值。方法回顾性分析2011年1月-9月IVF/ICSI-ET的458个周期。每个周期均采用黄体期长方案控制性促排卵。酶免疫化学发光法检测HCG日孕酮水平。将P浓度,分为6组:≤1.0、1.01-1.25、1.26-1.50、1.51-1.75、1.76-2.0、〉2.0,比较各组继续妊娠率。以1.0 ng/mL为界值点,分为≤1.0 ng/mL组151周期,〉1.0 ng/mL组307周期,比较两组间各项检测指标及妊娠结局。再以1.5为界值点,分为≤1.5 ng/mL组330周期、〉1.5 ng/mL组128周期,比较两组间各项检测指标及妊娠结局。结果 (1)6组继续妊娠率分别为44.4%,40.6%,43.4%,35.7%,36.3%,26.8%。不是任意两组间差异均有统计学意义(P〉0.05);(2)〉1.0 ng/mL组HCG日E2水平,获卵数较≤1.0 ng/mL组高,两组差异比较有统计学意义(P〈0.05),优胚数,临床妊娠率及继续妊娠率无统计学意义(P〉0.05);(3)〉1.5 ng/mL组HCC日E2水平,获卵数、临床妊娠率及继续妊娠率较≤1.5 ng/mL组高,有统计学意义(P〈0.05),优胚数无统计学意义(P〉0.05)。结论 HCG注射日P水平影响妊娠结局,最佳界值1.5 ng/mL。
出处 《浙江实用医学》 2012年第4期240-242,共3页 Zhejiang Practical Medicine
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