60例原发性阴道癌的放射治疗

RADIATION THERAPY IN PRIMARY CARCINOMA OF VAGINA——AN ANALYSIS OF 60 CASES

原发性阴道癌较为罕见,据我院统计,占女性生殖系统恶性肿瘤的0.7％。但阴道的继发性癌则较多见。本组60例原发性阴道癌,均系病变位于阴道,宫颈正常,并除外其他部位肿瘤的阴道转移。本文分析60例原发性阴道癌的放疗效果,并探讨其放疗方法。

From April 1974 to August 1985, 60 patients with primary carcinoma of vaginawere treated with radiotherapy in the Hospital. Most cases were squamous cell carcinoma.Cancer of upper third of the vagina were treated with techniques similar to those usedfor carcinoma of cervix. For lesions of middle or lower third of vagina, intracavitaryradium box (or new vaginal after loading applicator) combined with linear vaginal mouldwas used. A total dose of 70 Gy/5 wks was delivered to the base of the lesion. Externalirradiation in a dose of 40-50 Gy/4-5 wks was delivered to the mid-plane of pelvis. The 5year survival rates for stage Ⅰ, Ⅱ, Ⅲ and Ⅳ patients of this group were 100%,75.0%,50.0% and 0% respectiively. The authors believe that patients with lesion more than 3cmin diameter or squamous cell carcinoma grade Ⅲ treated with radiotherapy combinedwith cisplatin-related chemotherapy may have an improved survival rate.