影响儿童何杰金氏病放射治疗长期生存的因素

FACTORS INFLUENCING LONG TERM SURVIVAL OF CHILDREN DISEASE TREATED BY RADIOTHERAPY

我科自1960年～1984年共收治儿童何杰金氏病107例。现临床分析如下,试图从中找到影响患儿放射治疗长期生存的因素,并提出改进治疗方案。 临床资料 一、年龄性别 全部病例107例,失访3例,随访率97％。年龄2～15岁,平均9.36岁,2～5岁15例,占14％;6～10岁46例,占43％;

From 1960 through 1984,107 children with Hodgkin's disease were treated by radio-therapy. The end results were influenced by: 1. The younger the age, the worser theprognosis, 2. Histology type of NS had the best result, followed by LP, MC and LD.3. Mantle field or total-lymph-node irradiation was better than local-regional irradia-tion. 4. A total dose of 30-35 Gy was most suitable. 5. Combined chemotherapy andradiotherapy increased the survival time. 6. For stage Ⅱ cases, primary lesions locatedin cervical areas was better than in other locations. 7. First relapes after radiotherapycould be rescued by repeat radiotherapy and survival time could be prolonged.