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ω-3多不饱和脂肪酸对大电导钙离子激活钾通道的影响 被引量：4

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摘要 ω-3多不饱和脂肪酸主要包括二十碳五烯酸和二十二碳六烯酸,二十碳五烯酸和二十二碳六烯酸经细胞色素P450环氧化酶代谢可分别生成环氧二十碳四烯酸和环氧二十二碳五烯酸。环氧二十二碳五烯酸和环氧二十碳四烯酸可激活大电导钙离子激活钾通道,这可能是ω-3多不饱和脂肪酸扩张血管和降低血压的机制。
作者 季圆 吴莹 王如兴
机构地区 南京医科大学附属无锡人民医院心内科
出处 《中国心脏起搏与心电生理杂志》 2012年第4期357-359,共3页 Chinese Journal of Cardiac Pacing and Electrophysiology
基金 国家自然科学基金资助项目(项目编号:81070157) 江苏省自然科学基金资助项目(项目编号:BK2011179) 江苏省人事厅"六大人才高峰"第七批高层次项目(项目编号:006)
关键词 心血管病学 Ω-3多不饱和脂肪酸 综述 大电导钙离子激活钾通道 膜片钳 细胞色素P450
分类号 R331.38 [医药卫生—人体生理学]
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参考文献19

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二级参考文献3

共引文献10

同被引文献48

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中国心脏起搏与心电生理杂志
2012年 第4期

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