摘要
成年大鼠肝细胞通常很少分裂,但一旦肝组织部分切除或受到某些化学物质的攻击,随即可引起残留肝细胞再生,DNA合成旺盛及细胞分裂加剧。
C-ras-P21 and G-GT activity and G-GT isoenzymes in rat liver extracts weremeasured after partial hepatectomy. There were G-GT activity peaks at 12th and 36thhours after operation, while no distinct isoenzyme pattern was found. P21 proteinexpression occurred between 48 and96 hours after partial hepatectomy. These resultssuggest that the temporary increase of G-GT and P21 protein levels is involved inthe prereplicative stage of liver regeneration.
出处
《肿瘤》
CAS
CSCD
北大核心
1990年第2期62-63,共2页
Tumor
