椎管内血管外皮细胞瘤的诊治与预后分析

Research on treatment and prognosis of intraspinal hemangiopericytoma

目的回顾分析椎管内血管外皮细胞瘤诊治和预后,提升对该病的总体认识及诊疗水平。方法对我院神经外科收治的18例经病理证实椎管内血管外皮细胞瘤的病人进行回顾性分析及随访,分析其临床特点、诊治方法和预后。结果 18例均行手术治疗,其中7例全切,9例近全切,2例大部切,随访到12例,随访11～131个月(平均57个月),有9例术后行普通放疗,有5例死亡,其中2例发生转移,其余7例存活目前生活自理。5年存活率及复发率分别为87.5%,37.5%。结论椎管内血管外皮细胞瘤为恶性肿瘤,手术应尽量全切,术后建议行放疗。鉴于其易复发和转移,经积极治疗的患者术后仍应定期复查。

Objective To study the clinical diagnosis, treatment and prognosis of intraspinal hemangiopericytoma and improve the management of this disease. Methods The clinical data of 18 patients with intraspinal hemangiopericytoma confirmed by pathology were analyzed retrospectively, then the results were valued. Results Of 18 patients, 7 achieved totally resection, 9 sub-total resection and 2 gross resection. 12 patients were followed up from 11 to 131 months （mean 57 months）, 9 were given radiotherapy. 5 died and 2 of them metastasized. Other 7 respectively returned to daily life normally. The 5-year survival rate and recurrence rate was 87. 5% and 37. 5% respectively. Conclusions Intraspinal hem-angiopericytoma are malignant tumors. The tumor should be resected totally as far as possible ,then the radiotherapy was suggested. Long-term follow-up is essential because of easily recurrence and metastasis.