术后放疗在睾丸精原细胞瘤治疗中的作用

POST-OPERATIVE RADIOTHERAPY OF SEMINOMA OF THE TESTIS

本文报告我科收治38例睾丸精原细胞瘤术后放疗的随访结果,全组5年生存率为72.7％,其中Ⅰ期90.9％、Ⅱ期50.0％、Ⅲ期0％。放射剂量25—30Gy,对有巨大肿块者局部追加5—10Gy。照射野内无一例复发。鉴于本组8例Ⅱ期患者中有4例发生纵隔或左锁骨上转移,故对Ⅱ期以上患者,尚应予以纵隔和左锁骨上淋巴区预防性照射。对出现血行转移的患者进行积极的局部放疗也可获得较好的疗效。

Thirty-eight patients with seminoma of the testis were treated in our hospital fiom October 1975 to June 1986. According to the Walter Reed Hospital Staging classification, the 5-year Survival rate was 72.7％ for all stages, and 90.9％ (20/22) for stage Ⅰ, 50％ (4/8) for stage Ⅱ, 0％ (0/3) for stage Ⅲ. Radiation doses ranged from 25 to 30 GT and was boosed 5-10 Gy for large masses None occured tumor recurrence in irradiation fields. Of 8 patients with stage Ⅱ, 4 cases developed metastasis on mediatinun or supraclavicular regions. It is necessary that prophylactic (?)irradiation of the mediastinum and supraclavi-cular regions for stage Ⅱ patients with testicular seminoma. Better effect can be expected in patients with single pulmonary metastasis lesiou using local irradiation.