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Th17细胞和Treg细胞与银屑病关系的研究进展 被引量：6

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摘要 银屑病病因及发病机制复杂,但其核心是免疫功能异常,以T细胞为主的免疫功能紊乱在疾病发生中起重要作用,研究证实银屑病发病中存在Th1/Th2细胞平衡失调,且以Th1型反应为主。近年来研究发现两种与Th1细胞和Th2细胞不同的T细胞亚群Th17细胞与Treg细胞在银屑病发病中也起着重要作用。Th17细胞是近年来发现的一种新型CD4＋T细胞亚群,它通过分泌IL-17。
作者 蒋延伟 王忠永 邱会芬 孙程
机构地区 滨州医学院附属医院皮肤科
出处 《滨州医学院学报》 2012年第3期226-229,219,共5页 Journal of Binzhou Medical University
基金 山东省医药卫生科技发展计划(2011HW003)
关键词 TH17细胞 TREG细胞 银屑病 失衡
分类号 B846 [哲学宗教—心理学]
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参考文献27

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同被引文献57

  • 1郑敏.银屑病发病机制研究中若干问题的思考[J].中华皮肤科杂志,2006,39(3):121-123. 被引量：104
  • 2吴长有.Th17细胞:一种新的效应CD4^+T细胞亚群[J].细胞与分子免疫学杂志,2006,22(6):695-697. 被引量：36
  • 3张小娟,纪维,党文义,金汤.生物制剂治疗银屑病的进展[J].西北药学杂志,2007,22(3). 被引量：3
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滨州医学院学报
2012年 第3期

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