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放射治疗对涎腺和成体干细胞的影响 被引量：1

Influence of Radiotherapy on Salivary Glands and Adult Stem Cells
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摘要 头颈部肿瘤的放射治疗能得到较高的治愈率．因此放疗是目前头颈部肿瘤的主要治疗方法．但同时放疗会损伤涎腺，出现口腔干燥症等并发症，影响患者的生活，这是放疗中急需解决的问题。本文就放疗对涎腺及其干细胞的损伤及干细胞治疗予以综述。
作者 顾佳妹 苏俭生
机构地区 同济大学附属口腔医院修复科
出处 《口腔颌面外科杂志》 CAS 2012年第4期292-295,共4页 Journal of Oral and Maxillofacial Surgery
基金 国家自然科学基金资助项目(30840031 30970726)
关键词 放射治疗 涎腺 成体干细胞 radiotherapy salivary glands adult stem cells
分类号 R739.91 [医药卫生—肿瘤]
  • 相关文献

参考文献38

  • 1Peter LI, Withers HR. Applying radiobiological principles to combined modality treatment of head and neck cancer- the time factor [J]. Int J Radiat Oncol Biol Phys, 1997,39 (4):831-836.
  • 2沈春英,胡超苏,何少琴.头颈部恶性肿瘤放射治疗后唾液腺功能减退的防治[J].中华放射肿瘤学杂志,2003,12(B02):62-64. 被引量：4
  • 3Vissink A,Mitchell JB,Baum BJ,et al. Clinical management of salivary gland hypofunction and xerostomia in head- and-neck cancer patients: successes and barriers [J]. Int J Radiat Oncol Biol Phys,2010,78(4):983-991.
  • 4Eriksson D, Stigbrand T. Radiation-induced cell death mechanisms[J]. Tumour Biol,2010,31 (4):363-372.
  • 5Gresik EW. The granular convoluted tubule (GCT) cell of rodent submandibular glands [J]. Microsc Res Tech, 1994,27(1): 1-24.
  • 6Denny PC, Ball WD, Redman RS. Salivary glands: a paradigm for diversity of gland development [J]. Crit Rev Oral Biol Med,1997,8(1):51-75.
  • 7Grundmann O, Mitchell GC, Limesand KH. Sensitivity of salivary glands to radiation: from animal models to thera- pies[J]. J Dent Res,2009,88(10):894-903.
  • 8Tatsuishi Y, Hiyota M, Kishi T, et al. Human salivary gland stem/progenitor cells remain dormant even after irra- diation[J]. Int J Mol Med,2009,24(3):361-366.
  • 9Coppes RP, Meter A, Latumalea SP, et al. Defects in muscarinic receptor-coupled signal transduction in isolated parotid gland cells after in vivo irradiation: evidence for a non-DNA target of radiation [J]. Br J Cancer,2005,92(3): 539-546.
  • 10Eneroth CM, Henrikson CO, Jakobsson PA. Pre-irradiationqualities of a parotid gland predicting the grade of func- tional disturbance by radiotherapy [J]. Acta Otolaryngol, 1972,74(6):436-444.

二级参考文献30

  • 1Rhodus NL, Bereuter J. Clinical evaluation of a commercially available oral moisturizer in relieving signs and symptoms of xerostomia in postirradiation head and neck cancer patients and patients with Sjogren's syndrome. J Otolaryngol,2000,29:28-34.
  • 2Greer JE, Eltorky M, Robbins KT. A feasibility study of salivary gland autograft transplantation for xerostomia. Head Neck,2000,22:241-246.
  • 3Seikaly H, Jha N, Mcgaw T, et al. Submandibular gland transfer : a new method of preventing radiation-induced xerostomia. Laryngoscope,2001,111:347-352.
  • 4Jha N, Seikaly H, McGaw T, et al. Submandibular salivary gland transfer prevents radiation-induced xerostomia. Int J Radiat Oncol Boil Phys,2000,46:7-11.
  • 5Wu Q, Manning M, Schmidt-Ullrich R, et al. The potential for sparing of parotids and escalation of biologically effective dose with intensity-modulated radiation treatments of head and neck cancers:a treatment design study. Int J Radiat Oncol Biol Phys,2000,46:195-205.
  • 6Cheng JCH, Chao KSC, Low D. Comparison of intensity modulated radiation therapy (IMRT)treatment techniques for nasopharyngeal carcinoma. Int J Cancer, 2001, 96: 126-131.
  • 7Chao KSC, Deasy JO, Markman J, et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy:initial results. Int J Radiat Oncol Biol Phys,2001,49:907-916.
  • 8Johnstone PAS, Peng YP, May BC, et al. Acupuncture for pilocarpine-resistant xerostomia following radiotherapy for head and neck malignancies. Int J Radiat Oncol Biol Phys,2001,50:353-357.
  • 9Stephens LC, Schultheiss TE, Price RE, et al.Radiation apoptosis of serous acinar cells of salivary and lacrimal glands. Cancer,1991,67:1539-1543.
  • 10Nagler R, Marmary Y, Fox PC, et al. Irradiation-induced damage to the salivary glands:the role of radox-active iron and copper.Radiat Res,1997,147:468-476.

共引文献3

同被引文献26

  • 1Pringle S,Van Os R, Coppes RP. Concise review: adult salivary gland stem cells and a potential therapy for xerostomia[J]. Stem Cells, 2013,31:613-619.
  • 2Grundmann O, Mitchell GC, Limesand KH. Sensitivity of salivary glands to radiation: from animal models to therapies[J]. J Dent Res, 2009,88:894-903.
  • 3Li Y,Taylor JM,Ten Haken RK,et al.The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radi- ation therapy[J].Int J Radiat Oncol Biol Phys,2007,67: 660-669.
  • 4Medina VA,Prestifilippo JP,Croei M ,et al. Histamine prevents func- tional and morphological alterations of submandibular glands in- duced by ionising radiation [J]. Int J Radiat Biol,2011,87:284-292.
  • 5Tatsuishi Y, Hiyota M, Kishi T,et al. Human salivary gland stem/pro- genitor cells remain dormant even after irradiation[J]. Int J Mol Med, 2009,24:361-366.
  • 6Lombaert IM,Knox SM,Hoffman MP. Salivary gland progenitor cell biology provides a rationale for therapeutic salivary gland regenera- tion[J].Oral Dis,2011,17:445-449.
  • 7Neumann Y, David R, Stiubea-Cohen R,et al.Long-term cryop- reservation model of rat salivary gland stem cells for future therapy in irradiated head and neck cancer patients [J].Tissue Eng:Part C Methods,2012,18:710-718.
  • 8Lombaert IM, Brunsting JF, Wierenga PK ,et al.Rescue of salivary gland function after stem cell transplantation in irradiated glands[J]. PLoS One, 2008,3:e2063.
  • 9Feng J, van der Zwaag M, Stokman MA,et al.lsolation and character- ization of human salivary gland cells for stem cell transplantation to reduce radiation-induced hyposalivation[J]. Radiother Oncol,2009, 92:466-471.
  • 10Gorjup E, Danner S, Rotter N,et al. Glandular tissue from human pancreas and salivary gland yields similar stem cell populations[J].Eur J Cell Biol,2009,88:409-421.

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口腔颌面外科杂志
2012年 第4期

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