脉搏波传导速度联合心电图检测在冠心病筛查中的价值

Predictive Value of Pulse Wave Velocity Combined with ECG in the Diagnosis of Coronary Heart Disease

目的探讨臂踝脉搏波传导速度(PWV)联合心电图检测在冠状动脉粥样硬化性心脏病(简称冠心病)筛查中的应用价值。方法选择住院并行冠状动脉造影的患者452例,根据冠状动脉造影结果,将入选患者分为冠心病组(251例)和非冠心病组(201例),所有入选患者在冠状动脉造影前应用脉搏波速度测量系统测量臂踝脉搏波传导速度(baPWV)、baPWV%和心电图;以冠状动脉造影为金标准,应用诊断试验方法评价baPWV%联合心电图对冠心病的筛选价值。结果单独应用BaPWV%时,其灵敏度为60.6%,特异度为75.2%;单独应用心电图时,其灵敏度为60.9%,特异度为87.5%;baPWV%与心电图并联监测时,其灵敏度为85.6%,特异度为63.4%。结论 baPWV%与心电图并联监测冠心病时,其敏感性显著提高,在冠心病的筛查中具有重要的应用价值。

Objective To explore the predictive value of brachial-ankle pulse wave velocity（PWV）combined with ECG in the diagnosis of coronary atherosclerotic heart disease.Methods 452 patients who were hospitalized were recruited,and divided into coronary heart disease（CHD）group（251 cases）and non-CHD group（201 cases）according to coronary angiography（CAG）.All patients of CHD were measured with baPWV,baPWV% and ECG.According to the Golden Standard（CAG）,diagnosis trial method was applied to calculate specificity,sensitivity and other index concerned.Results A moderate sensitivity（60.6%）and a moderate specificity（75.2%）of baPWV% were found.A moderate sensitivity（60.9%）and a higher specificity（87.5%）of ECG were found.An obvious higher sensitivity（85.6%）and a moderate specificity（63.4%）of baPWV% combined with ECG were found.Conclusion Combining baPWV% with ECG to predict CHD has a significant value in screening patients of CHD with a significantly increased sensitivity.