脑梗死与颈动脉粥样硬化及相关危险因素分析

Analysis on Cerebral Infarction and Carotid Atherosclerosis and Related Risk Factors

目的探讨脑梗死与颈动脉粥样硬化及其危险因素与斑块发生的关系。方法将279例患者分为斑块组201例,非斑块组78例,所有患者都记录既往有或无无高血压、糖尿病、高脂血症及吸烟、饮酒史,并进一步检测血糖及糖耐量、三酰甘油、胆固醇、低密度脂蛋白胆固醇及血压,行颈动脉超声检查及头颅磁共振成像检查,通过数据统计分析脑梗死和颈动脉粥样硬化及其危险因素与斑块发生的关系。结果脑梗死组颈动脉粥样硬化斑块发生明显增多(P<0.01);与无斑块组比较,年龄、吸烟、脑梗死、高血压、三酰甘油、胆固醇及低密度脂蛋白胆固醇增高、糖尿病是颈动脉硬化的主要危险因素(P<0.01或P<0.05),差异有统计学意义。结论颈动脉粥样硬化与脑梗死的关系密切,吸烟、高血压、脂代谢异常、糖尿病是颈动脉硬化的主要危险因素。

Objective To discuss cerebral infarction and carotid atherosclerosis,and the correlation between its risk factors and plaque incidence.Methods 279 cases were divided into plaque group of 201 cases,non plaque group of 78 cases.All patients were recorded of hypertension,diabetes,history of hyperlipidemia,and smoking,drinking history,and further detection of glucose and glucose tolerance,TG,TC and LDL-cholesterol,blood pressure,carotid ultrasonography and MRI scan were done,correlation between cerebral infarction and carotid atherosclerosis and its risk factors and the occurrence of plaque was analyzed by the statistics.Results Cerebral infarction incidence was significantly higher in carotid atherosclerosis plaque group(P≤0.01);compared to the no plaque group,age,smoking,hypertension,stroke,TG,TC and LDL-cholesterol were higher,diabetes is the major risk factors of carotid artery atherosclerosis(P≤0.01or P≤0.05),the difference was statistically significant.Conclusion Relationship between carotid atherosclerosis and cerebral infarction is close,smoking,hypertension,abnormal lipid metabolism,diabetes mellitus are the major risk factors of carotid atherosclerosis.