摘要
以L-苹果酸为模板分子,丙烯酰胺(AA)、乙二醇二甲基丙烯酸酯(EGDMA)分别为功能单体和交联剂,采用沉淀聚合法制备了分子印迹聚合物微球,研究了聚合体系组成对模板聚合物吸附特性的影响。实验表明,以1∶4∶20的物质的量比加入模板分子、AA和EGDMA时,制备的模板聚合物吸附容量高,印迹效果好。通过Scat-chard分析研究了聚合物的选择结合性能,结果表明分子印迹聚合物微球在识别L-苹果酸的过程中存在2类结合位点,而空白印迹聚合物微球只存在1类结合位点。印迹聚合物微球对L-苹果酸和D-苹果酸的手性分离因子α达2.05。
L-malic acid imprinted polymer microspheres were prepared by precipitation polymerization, using AA as functional monomer and Using EGDMA as crosslinker. The effects of the composition of polymerization sys- tems on the adsorption property of MTP were studied. The results indicate that the imprinted polymer microspheres prepared with the molar ratio of n（L-malic acid） ： n（AA） .＂ n（EGDMA）=I ＂ 4 ＇ 20 added in the polymerization, exhibite advantageous characteristics of high binding activity and optimal imprinting effect. Scatchard analysis suggest that there are two classes of binding sites in the imprinted polymer mierospheres and only one class in the blank polymer mierospheres. The imprinted polymer microspheres exhibit an excellent stereoselectivity for L-malic acid and Dmalic acid with the separation factor 2. 05.
出处
《材料导报》
EI
CAS
CSCD
北大核心
2012年第16期51-54,70,共5页
Materials Reports
基金
辽宁省教育厅科学技术研究资助项目(L2010047
10052)
关键词
L-苹果酸
分子印迹聚合物微球
沉淀聚合
分子识别
L-malic acid, molecularly imprinted microspheres, precipitation polymerization, molecular recogni-tion
