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过敏体质母亲母乳喂养与婴幼儿患呼吸道合胞病毒性毛细支气管炎的相关性研究

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摘要 目的:观察不同体质母亲母乳喂养与婴幼儿患呼吸道合胞病毒(RSV)毛细支气管炎的相关性。方法:检测过敏体质母亲初乳细胞因子TGF-β1、IL-10、IL-4水平,同时追踪其喂养儿RSV毛支患病率,并检测RSV毛支患儿外周血细胞因子TGF-β1、IL-10、IL-4水平,同期收集非过敏体质母亲初乳及其母乳喂养儿外周血作对照。结果:过敏体质母亲初乳细胞因子TGF-β1水平显著低于非过敏体质母亲初乳(P<0.05),IL-4水平则显著高于非过敏体质母亲初乳(P<0.05),IL-10水平在两者之间无统计学差异(P>0.05);过敏体质母亲母乳喂养儿RSV毛支患病率显著高于非过敏体质母亲母乳喂养儿(P<0.05);过敏体质母亲母乳喂养的RSV毛支患儿外周血细胞因子TGF-β1、IL-10水平显著低于非过敏体质母亲母乳喂养的RSV毛支患儿(P<0.05),而IL-4水平则显著高于非过敏体质母亲母乳喂养的RSV毛支患儿(P<0.05)。结论:过敏体质母亲母乳喂养可能会导致喂养儿易患RSV毛支。
出处 《中国妇幼保健》 CAS 北大核心 2012年第26期4128-4130,共3页 Maternal and Child Health Care of China
基金 山东省自然科学基金资助项目〔ZR2009CL007〕
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