期刊文献+

重视脑白质高信号的异质性和临床重要性 被引量:14

原文传递
导出
摘要 脑白质高信号(white matter hyperintensities,WMHs),表现为在磁共振T2加权或液体衰减反转恢复序列(FLAIR)上,双侧侧脑室周围或皮质下白质多发的点状、斑片状或融合性高信号。WMHs也被称脑白质疏松,是由Hachinski等在1987年首次提出,用来描述脑皮质下白质的异常CT表现,即白质密度减低。WMHs普遍存在于老年人群中,据统计,60~70岁的人群中80%以上患有WMHs,而到80~90岁则几乎可达100%,因此常常被认为是一种老龄化现象,被许多医生所忽视。
作者 楼敏 严慎强
出处 《中华医学杂志》 CAS CSCD 北大核心 2012年第31期2165-2167,共3页 National Medical Journal of China
  • 相关文献

参考文献20

  • 1Hachinski VC, Potter P, Merskey H. Leuko-araiosis. Arch Neurol, 1987,44:21-23.
  • 2de Leeuw FE, de Groot JC, Achten E, et al. Prevalence ofcerebral white matter lesions in elderly people : a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurel Neurosurg Psychiatry,2001,70:9-14.
  • 3Inzitari D. Leukoaraiosis: an independent risk factor for stroke? Stroke ,2003,34:2067-2071.
  • 4Pantoni L. Leukoaraiosis : from an ancient term to an actual marker of poor prognosis, Stroke, 2008,39 : 1401-1403.
  • 5Debette S, Markus HS. The clinical importance of white matter hypefintensities on brain magnetic resonance imaging: systematic review and meta-analvsis. BMJ.2010.341 :c3666.
  • 6Pantoni L. Cerebral small vessel disease:from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol, 2010,9:689-701.
  • 7Schmidt R, Schmidt H, Haybaeck J, et al. Heterogeneity in age- related white matter changes. Acta Neuropathol, 2011,122 : 171- 185.
  • 8Soriano-Raya JJ, MiralbeU J, Lopez-Cancio E, et al. Deep versus periventricular white matter lesions and cognitive function in a community sample of middle-aged participants. J Int Neuropsychol Soc ,2012, [ Epub ahead of print ].
  • 9Gouw AA, van de/ Flier WM, Fazekas F, et al. Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability Study. Stroke, 2008,39 : 1414-1420.
  • 10Schmidt R, Enzinger C, Ropele S, et al. Progression of cerebral white matter lesions: 6-year results of the Austrian Stroke Prevention Study. Lancet,2003,361:2046-2048.

同被引文献176

引证文献14

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部