期刊文献+

围术期布托啡诺预先镇痛预防骨关节病患者术后长期慢性疼痛的效果

Effects of perioperative preemptive analgesia with butorphnol on preventing chronic pain after the bone- joint operation in a long term period
原文传递
导出
摘要 目的观察围术期布托啡诺预先镇痛对预防骨关节病患者术后长期慢性疼痛的效果。方法择期行骨关节手术的患者40例,随机分为A组(预先镇痛组)、B组(对照组),每组20例。A组患者从术前30min开始,静脉给予布托啡诺30μg/kg,每间隔4h重复1次,直到术后72h;B组患者围术期不做特殊的处理,只在术后患者主诉疼痛难忍时给予布托啡诺30μg/kg。出院后1年内对两组患者每月随访1次。结果A组患者术后发生骨关节疼痛的例数、VAs评分、需要口服镇痛药缓解疼痛的例数及其剂量均少于B组(P〈o.05)。结论围术期布托啡诺预先镇痛可降低骨关节病术后长期慢性疼痛的发生率和疼痛程度。 Objective To observe the effects of perioperative preemptive analgesia with butor- phnol on preventing chronic pain after the bone-joint operation. Methods Forty patients undergoing selective bone-joint operation were randomly divided into two groups, group A (butorphnol group) and group B (control group), 20 patients in each group. The patients were given butorphanol 30 μg/kg before the operation and repeated every 4 hours, lasting to 72 hours after the operation in group A. The patients were received nothing except butorphanol 30 μg/kg when the patients could not bear the pain in group B. The patients were followed-up every month until one year. Results The number of patients appearing chronic pain,VAS, necessary to take analgesics and its dose in group A were all less than those in group B (P〈0.05). Conclusion The perioperative preemptive analgesia with bu- torphanol can effectively prevent chronic pain after the bone-joint operation in a long term period.
出处 《实用疼痛学杂志》 2012年第3期193-195,共3页 Pain Clinic Journal
关键词 布托啡诺 预先镇痛 疼痛 慢性病 Butorphanol Preemptive analgesia Pain Chronic disease
  • 相关文献

参考文献6

二级参考文献67

  • 1徐建国.慢性疼痛的药物治疗进展[J].医学研究生学报,2007,20(2):113-115. 被引量:43
  • 2张文祥,倪家骧.臭氧在疼痛治疗中的应用[J].中国疼痛医学杂志,2007,13(1):46-48. 被引量:26
  • 3石玉生.神经妥乐平在神经病理性疼痛的临床应用[J].中国疼痛医学杂志,2007,13(1):57-58. 被引量:21
  • 4何睿林,蒋宗滨,黎承润,唐秀行,唐小松.神经妥乐平肌内注射治疗神经源性疼痛的临床观察[J].中国疼痛医学杂志,2007,13(2):76-78. 被引量:21
  • 5Merskey H, Bogduk H. Classification of chronic pain : descriptions of chronic pain syndromes and definitions of pain terms. Seattle : IASP Press, 1994.
  • 6Kehlet H, Jensen, T, Clifford W. Persistent postsurgical pain : risk factors and prevention. Lancet,2006,367:1618-1625.
  • 7Jung BF, Ahrendt GM, Oaklander AL, et al. Neuropathic pain following breast cancer surgery: proposed classification and research update. Pain ,2003,104 : 1-13.
  • 8Sorkin LS ,Xiao WH ,Wagner R, et al. Tumour necrosis factor alpha induces ectopic activity in nociceptive primary afferent fibres. Neuroscience, 1997,81:255-262.
  • 9Gold MS, Weinreich D, Kim C S, et al. Redistribution of Na(V) 1.8 in uninjured axons enables neuropathic pain. J Neurosci ,2003,23 : 158-166.
  • 10Koltzenburg M. Painful neuropathies. Curr Opin Neurol, 1998,11 : 515-521.

共引文献159

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部