摘要
针对环咽肌失弛缓导致的吞咽障碍难以精确评价和准确治疗的问题,以超弹性膨胀气囊受力变形分析为基础,设计开发了环咽肌压力测量及扩张治疗装置。研究表明,膨胀气囊外部压力与充气体积、气囊内压、材料性能、结构尺寸存在着明确的非线性关系,进而利用多元回归分析确定治疗装置中膨胀气囊外部压力(环咽肌对气囊压力)与气囊内压、加压容器体积改变量之间的函数关系式,将环咽肌压力测定转化为充气压力与体积的测量问题。力学验证实验表明,环咽肌压力测量及扩张治疗装置简单可靠、测量结果准确有效,可用于环咽肌失弛缓吞咽障碍程度的精确评定,并为患者提供准确的、个性化的治疗方案。
In order to explore the quantification method and accurate therapy of dysphagia induced by cricopharyngeal achalasia,the cricopharyngeal pressure measurement and therapeutic instrument were designed based on the deformation analysis of a hyperelastic expansion air bag.According to nonlinear relationship among the external pressure of catheter sacculus,the internal pressure of sacculus and the volume change of closed pressure vessel,a relation function of those variables was decided by multiple regression analysis.Experimental results show that the measurement instrument of cricopharyngeal pressure is effective and exact,so individual therapeutic scheme can be provided for the patient of cricopharyngeal achalasis.
出处
《实验力学》
CSCD
北大核心
2012年第4期474-479,共6页
Journal of Experimental Mechanics
基金
江西省科技厅重点课题(赣财政[2008]147号)
江西省高等学校教改课题(JXJG-10-1-17)
关键词
环咽肌失弛缓
吞咽障碍
压力测量
扩张治疗
膨胀气囊
cricopharyngeal achalasis
dysphagia
pressure measurement
expansion therapeutics
sacculus
