丙泊酚静脉麻醉与异氟醚吸入麻醉在巴马小型猪实验中的比较

Comparative of Propofol Intravenous Anesthesia and Isoflurane Inhalation Anesthesia in Bama Minipigs

目的比较丙泊酚静脉麻醉与异氟醚吸入麻醉在巴马小型猪实验中的麻醉效果。方法巴马小型猪10头,平均分成2组,分别进行丙泊酚静脉麻醉和异氟醚吸入麻醉,并于术前、术中及术后对其进行麻醉监测。结果两组实验猪的数量、体重、手术时间和麻醉时间无显著性差异(P>0.05);异氟醚组恢复自主呼吸的时间短于丙泊酚组(P<0.05);与基础值相比,各组实验猪在麻醉后HR值均明显升高(P>0.01),MAP值降低明显(P>0.01);但各组间及组内SPO2和PH值差异不显著(P>0.05)。结论丙泊酚静脉麻醉应根据手术过程中实验动物的反应情况适当调整丙泊酚泵入量;而异氟醚吸入麻醉的麻醉过程平稳,麻醉效果好,术后苏醒快,适合情况复杂且时间较长的手术。

Objective To compare Comparative study of propofol intravenous anesthesia and isoflurane inhalation anesthesia in Bama Minipigs.Methods Bama Minipigs 10,the average into two groups are propofol intravenous anesthesia and isoflurane inhalation anesthesia,and in preoperative,preoperative and postoperative the anesthesia monitoring.Results Two groups of weight number of pigs,operation time and anesthesia time no significant difference of difference（P〉0.05）;Different fluorine ether group restore spontaneous breathing a short time in propofol group（P〈0.05）;Compared with the basic value,the experiment in anesthesia pig increased significantly after all HR value（P〉0.01）,reduce the MAP is obvious（P〉0.01）;But each rooms and in the group SPO2 and PH value difference was not significant（P〉0.05）.Conclusion Propofol intravenous anesthesia during the operation should be based on the experimental animals of the reaction conditions appropriate adjustments propofol pump into the concentration;and different fluorine ether inhaled anesthesia during the procedure of smooth,anaeesthetic effect is good,postoperative came quickly,suitable for complicated cases,and the time is long operation.