期刊文献+

DNA甲基化修饰与代谢相关疾病的关系及运动干预展望 被引量:1

下载PDF
导出
摘要 随着社会的发展和人民生活水平的不断提高.人们的饮食与生活习惯都发生了巨大的变化。伴随发生的是人群肥胖、高脂血症和2型糖尿病(T2DM)等代谢性疾病的发病率迅速上升且患病人群年轻化,严重威胁着人类的健康和生活质量。
出处 《中国运动医学杂志》 CAS CSCD 北大核心 2012年第8期736-739,共4页 Chinese Journal of Sports Medicine
基金 国家自然科学基金(31100856)
  • 相关文献

参考文献32

  • 1Wenying Yang,Juming Lu,Jianping Weng,et al. Prevalence of diabetes among men and women in China. N Engl J Med,2010,362 : 1090 - 1101.
  • 2Kanai Y,Ushijima S,Kondo Y,et al. DNA methyltrans- ferase expression and DNA methylation of CpG island and pericentromeric satelliteregioninhumancolorectaland stom- ach cancers.Int J Cancer, 2001,91 : 205 - 212.
  • 3Rein T, DePamphilis ML,Zorbas H. Identifying 5-methyl- cytosine and related modifications in DNA genomes. Nucleic Acids Res, 1998,26 : 2255 - 2264.
  • 4Bird A. Katari S,Turan N,et al. DNA methylation and gene. Nature,2007,447:396 - 398.
  • 5Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA, 2005,102 : 10604 - 10609.
  • 6Sutherland JE,Costa M. Epigenetics and the environment Aead Sci,2003,983 : 151 - 160.
  • 7Anway MD,Cupp AS,Uzumeu M,et al. Epigenetic trans- generational actions of endocrine disruptors and male fertility. Science ,2005,308 : 1466 - 1469.
  • 8Weaver IC,Cervoni N,Champagne FA,et al. Epigenetic programming by maternal behavior. Nat Neurosei,2004,7: 847 - 854.
  • 9Zhou SS, Zhou YM,Li D,et al: Dietary methyl-consuming compounds and metabolic syndrome. Hypertens Res, 2011,34(12) : 1239 - 1245.'.
  • 10Waterland RA. Do maternal methyl supplements in mice affect DNA methylation of offspring? J Nutr,2003,133: 238 - 239.

二级参考文献86

  • 1Zick Y. Ser/Thr phosphorylation of IRS proteins : a molecular basis for insulin resistance. Sci STKE, 2005, 2005 (268): 4.
  • 2Zick Y. Uncoupling insulin signaling by serine/threonine phosphorylation : a molecular basis for insulin resistance. Biochem Soc Trans, 2004, 32:812-816.
  • 3Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signaling pathways : insights into insulin action. Nat Rev Mol Cell Bioh 2006, 7 (2): 85-96.
  • 4Glynn EL, Lujan HL, Kramer VJ, et al. A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle. Appl Physiol Nutr Metab, 2008, 33 ( 1 ): 93-101.
  • 5Musi N, Yu H, Goodyear LJ. AMP-activated protein kinase regulation and action in skeletal muscle during exercise. Biochem Soc Trans, 2003, 31 (Pt 1) : 191-195.
  • 6Fernando P, Bonen A, Hoffman-Goetz L. Predicting submaximal oxygen consumption during treadmill running in mice. Can J Physiol Pharmacol, 1993,71 ( 10-11 ):854-857.
  • 7Hawley JA, Lessard SJ. Exercise training-induced improvements in insulin action. Acta Physiol (Oxf), 2008, 192 (1) : 127-135.
  • 8Combettes-Souverain M, Issad T. Molecular basis of insulin action. Diabetes Metab, 1998, 24 (6) : 477-489.
  • 9Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature, 1994, 372 (6505) : 425-432.
  • 10Iwatsuka H, Shino A, Suzuoki Z. General survey of diabetic features of yellow KK mice. Endocrinol Jpn, 1970, 17 (1): 23-35.

共引文献4

同被引文献31

  • 1Xu Y.Wang L,He J,et al.Prevalence and control of diabetes in Chinese adults.JAMA,2013,310(9):948-959.
  • 2Langenberg C,Sharp SJ,Franks PW.et al.Gene-lifestyle interaction and type 2 diabetes;the EPIC interact casecohort study.PLoS Med,2014,11(5):el001647.
  • 3Bouchard L.Rabasa-Lhoret R,Faraj M,et al.Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction.Am J Clin Nutr,2010,91(2):309-320.
  • 4Nitert MD.Dayeh T,Volkov P.et al.Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes.Diabetes,2012,61(12)-.3322-3332.
  • 5Ronn T.Volkov P.Daveg'ardh C,et al.A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.PLoS Genet,2013,9(6):el003572.
  • 6Hanson M.Godfrey KM.Lillycrop KA.et al.Developmental plasticity and developmental origins of noncommunicable disease:theoretical considerations and epigenetic mechanisms.Prog Biophys Mol Biol,2011,106(1):272-280.
  • 7Michels KB,Harris HR.Barault L.et al.Birthweight,maternal weight trajectories and global DNA methylation of LINE-1 repetitive elements.PLoS One,2011,6(9):e25254.
  • 8Jaenisch R,Bird A.Epigenetic regulation of gene expression how the genome integrates intrinsic and environmental signals.Nat Genet,2003,33(Suppl):245-254.
  • 9Tammen SA.Friso S.Choi SW.Epigenetics:the link between nature and nurture.Mol Aspects Med,2013,34(4):753-764.
  • 10Hirst M.Marra MA.Epigenetics and human disease.Int J Biochem Cell Biol,2009,41(1):136-146.

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部