神经节苷脂联合高压氧治疗一氧化碳中毒迟发性脑病疗效分析

Delayed encephalopathy curative effect analysis of ganglion glucoside ester and hyperbaric oxygen therapy for carbon monoxide poisoning

目的探讨神经节苷脂联合高压氧治疗急性一氧化碳中毒迟发性脑病的临床疗效。方法将78例急性一氧化碳中毒迟发性脑病患者随机分为两组,治疗组及对照组各39例。对照组给予高压氧等常规治疗措施,治疗组在常规治疗基础上加用神经节苷脂,两组均治疗14d。结果治疗组总有效率为87.18%,对照组总有效率为71.80%,两组疗效比较差异有统计学意义(P<0.05)。结论在常规高压氧治疗基础上加用神经节苷脂,能明显提高疗效,有效改善一氧化碳中毒迟发性脑病患者的预后。

Objective To investigate the clinical efficacy of ganglioside and hyperbaric oxygen treatment of acute carbon monoxide poisoning with delayed encephalopathy. Methods 78 cases of patients with delayed encephalopathy were randomly divided into two groups,treatment group and control group,each group with 39 cases.The control group received the conventional treatment of hyperbaric oxygen and treatment group was added the ganglioside on the basis of conventional therapy.All patients were treated 14 d. Results The total efficiency rate of treatment group was 87.18%,and the control group was 71.80%, there was significant difference between the two groups （P 〈 0 05）. Conclusion Conventional hyperbaric oxygen therapy combined with ganglioside,can significantly improve the prognosis of patients with delayed encephalopathy after carbon monoxide poisoning.