IADPSG标准诊断妊娠糖尿病患者(GDM)112例临床疗效分析

Clinical analysis of 112 cases of IADPSG diagnostic criteria of gestational diabetes mellitus

目的探讨IADPSG标准诊断妊娠期糖尿病临床疗效。方法对于我院产检孕妇进行血糖筛查试验,阳性者进行葡萄糖耐量试验(OGTT)。按照NDDG和IADPSG两种诊断标准对孕妇进行诊断并分组,按照IADPSG标准共诊断GDM患者112例,给予临床干预后,其母婴结局与NDDG标准诊断的GDM患者90例进行比较。结果两组OGTT空腹值、糖化血红蛋白值比较,差异有统计学意义(P<0.05),两组的妊娠期高血压疾病、羊水过多、胎膜早破、胎儿生长受限、新生儿高胆红素血症的发生率、早产儿率及新生儿转科率比较,差异无统计学意义(P>0.05),而IADPSG组的剖宫产率、巨大儿比率、新生儿平均出生体重儿显著低于NDDG组(P<0.05)。结论采用IADPSG诊断标准可有效改善GDM患者的母婴结局。

Objective ： To study the influence of IADPSG diagnostic criteria of gestational diabetes mellitus on pregnancy outcome. Methods： Pregnant women received 50 g glucose screening test （GST）. Positive subjects received a 75 g oral glucose tolerance test （OGTT）. The diagnosis of GDM were according to two diagnostic criteria： NDDG and IADPSG. The outcomes of the mother and the neonate of the two groups were compared. Results： 90 cases met NDDG criterion, 112 cases met the IADPSG criterion. Fasting plasma glucose and glycosylated hemoglobin value of two groups were significant difference （ P 〈 0. 05 ）. There was no significant difference in the incidence of preeclampsia, polyhydramnios, fetal growth restriction, and premature rupture between the two groups （P 〉 0.05 ）. The rate of cesarean section, macrosomia ratio and the average birth weight of NDDG group were significantly higher than that of 1ADPSG group （P 〈 0. 05）. Conclusion ： IADPSG criterion can effectively reduce the incidence of adverse pregnancy outcomes.