头孢克肟的合成与研究

Synthesis and Study of Cefixime

头孢克肟,即第三代口服头孢菌素类抗生素,其具有通过对细胞分裂时细胞壁合成进行抑制的杀菌作用。且由于具有能够稳定的对多数B-内酰胺酶产生作用,广谱抗菌并且具有较长的半衰期、疗效好、适应症广、用药剂量小的优点而在临床中广泛运用。通过对头孢克肟的合成工艺进行研究。

The Cefixime,namely the third generation of oral cephalosporin antibiotics, it has the through to the division of the cell wall undertake inhibition synthesis fully antiseptic effect. And because it also has to stable on B - gave n - phenylimide enzyme action, broad - spectrum, has a long half - life, and has good curative effect, indications wide, the dosage of. In this paper, the preparation process of the latter of small advantages in clinical and extensive use cephalosporins.