植物类中药寒热药性与有机成分化合物次级基团相关性的文献研究

Literature study on the relationship between the cold-heat nature of Chinese medicine and the secondary structure groups of chemical constituents

目的:探寻植物类中药中有机成分化合物次级基团与植物类中药寒热属性的相关性。方法:利用现有文献提供的信息资料,通过文献检索收集植物类中药化学成分信息,利用化学信息学对资料进行整理,运用多种数据统计分析与挖掘方法分析化学信息数据,建立Logistic回归方程,对植物类中药寒热属性进行判别。结果:以有机成分化合物次级基团建立的Logistic回归方程,可以对植物类中药的寒热属性进行判别。结论:植物类中药寒热药性与有机成分具有相关性。

Objectives： Study on the relationship between the cold-heat nature of Chinese medicine and the secondary structure groups of chemical constituents. Methods： Use the information from existing literatures; Collect chemical information of herbal medicine by document retrieval. Then use chemical informatics to collate the data and analyze it. Establish Logistic regression equation based on the secondary structure groups of chemical constituents. Use the regression equation to distinguish cold-heat nature of herbs. Results： The Logistic regression equation could distinguish cold and heat of herbs. Conclusion： There is a correlation between cold-heat nature of Chinese medicine and organic constituents.