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硫化氢在心力衰竭干预中的作用 被引量:4

Role of hydrogen sulfide in heart failure
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摘要 目前临床上对心力衰竭的防治还没有较好的策略。H2S是一种具有多种生理学功能的内源性气体信号分子,且具有心肌保护功能。H2S对动脉粥样硬化、心肌肥大、氧化应激和同型半胱氨酸的影响,以及它在心力衰竭中的作用越来越受到人们的关注。 In recent years,few improved methods for prevention and treatment of heart failure have emerged.Hydrogen sulfide(H2S) is a new signal molecule,which has many biological roles,some especially relevant to cardiovascular protection.Clinicians and researchers have paid much attention to the effects of H2S on atherosclerosis,myocardial hypertrophy,oxidative stress and homocysteine levels as mediators of the role of H2S in heart failure. 更多还原
出处 《国际病理科学与临床杂志》 CAS 2012年第4期316-319,共4页 Journal of International Pathology and Clinical Medicine
基金 国家自然科学基金(811702777)~~
关键词 硫化氢 氧化应激 同型半胱氨酸 心力衰竭 hydrogen sulfide; oxidative stress; homolysteine; heart failure
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参考文献30

  • 1Fiorucci S, Distrutti E, Cirino G, et al.The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver[J]. Gastroenterology, 2006, 131(1):259-271.
  • 2Li L, Moore P. Putative biological roles of hydrogen sulfide in health and disease:A breath of not so fresh air?[J]. Trends Pharmacol Sci, 2008, 29(2):84-90.
  • 3Szabo C.Hydrogen sulphide and its therapeutic potential[J]. Nat Rev Drug Discov, 2007, 6(11):917-93S.
  • 4Shibuya N, Tanaka M, Yoshida M, et al. 3-Mercaptopyruvate sulfurtransferase produces hydro-gen sulfide and bound sulfane sulfur in the brain[J]. Antioxid. Redox Signal, 2009, 11(4):703-714.
  • 5Shibuya N Mikami Yj Kimura Y, et al. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide[J].J Biochem, 2009, 146(5):623-626.
  • 6田云朋,王虹艳,曲鹏,牛楠,陈亮.老年缺血性心力衰竭患者血浆硫化氢水平变化[J].中华高血压杂志,2011,19(6):578-580. 被引量:9
  • 7Emmanuele di V, Bianca R. Hydrogen sulfide as a mediator ofhuman corpus cavernosumsmooth-muscle relaxation[J]. Proc Natl Acad Sci USA, 2009, 106(11):4513-4518.
  • 8John W, Arun R, David J, et al. Ischemia-induced heart failure in mice genetic and pharmacologic hydrogen sulfide therapy attenuate [J]. Circulation, 2010, 122(1):11-19.
  • 9Galkina E, Ley K. Immune and inflammatory mechanisms of atherosclerosis [J]. Annu Rev Immunol, 2009, 27(1):165-197.
  • 10Zhao ZZ Wang Z, Li GH, et al. Hydrogen sulfide inhibits macrophage-derived foam cell formation [J]. Exp Biol Med, 2011, 236(2):169-176.

二级参考文献50

共引文献77

同被引文献53

  • 1Neil Kaplowitz.Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injury[J].World Journal of Gastroenterology,2004,10(12):1699-1708. 被引量:63
  • 2周小琴,成蓓,袁永辉.ATP结合盒转运子A1对巨噬细胞载脂蛋白E分泌的调节作用[J].中国病理生理杂志,2004,20(7):1149-1152. 被引量:1
  • 3Yanfei Wang,Xia Zhao,Hongfang Jin,Hongling Wei,Wei Li,Dingfang Bu,Xiuying Tang,Yali Ren,Chaoshu Tang,Junbao Du.Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice[J]. Arteriosclerosis, Thrombosis, and Vascular Biology . 2009 (2)
  • 4Suowen Xu,Zhiping Liu,Peiqing Liu.Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis[J]. International Journal of Cardiology . 2014
  • 5Sisi Lin,Chun Zhou,Edward Neufeld,Yu-Hua Wang,Suo-Wen Xu,Liang Lu,Ying Wang,Zhi-Ping Liu,Dong Li,Cuixian Li,Shaorui Chen,Kang Le,Heqing Huang,Peiqing Liu,Joel Moss,Martha Vaughan,Xiaoyan Shen.BIG1, a Brefeldin A–Inhibited Guanine Nucleotide-Exchange Protein Modulates ATP-Binding Cassette Transporter A-1 Trafficking and Function[J]. Arteriosclerosis, Thrombosis, and Vascular Biology . 2013 (2)
  • 6Roshni R. Singaraja,Henk Visscher,Erick R. James,Angeliki Chroni,Jonathan M. Coutinho,Liam R. Brunham,Martin H. Kang,Vassilis I. Zannis,Giovanna Chimini,Michael R. Hayden.Specific Mutations in ABCA1 Have Discrete Effects on ABCA1 Function and Lipid Phenotypes Both In Vivo and In Vitro[J]. Circulation Research . 2006 (4)
  • 7P. Kamoun.Endogenous production of hydrogen sulfide in mammals[J]. Amino Acids . 2004 (3)
  • 8Junbao Du,Yan Hui,Yiufai Cheung,Geng Bin,Hongfeng Jiang,Xiaobo Chen,Chaoshu Tang.The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells[J]. Heart and Vessels . 2004 (2)
  • 9Lingyun Wu,Wei Yang,Xuming Jia,Guangdong Yang,Dessislava Duridanova,Kun Cao,Rui Wang.Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats. Laboratory Investigation . 2008
  • 10Liping Fang,Hong Li,Chaoshu Tang,Bin Geng,Yongfen Qi,Xinmin Liu.Hydrogen sulfide attenuates the pathogenesis of pulmonary fibrosis induced by bleomycin in rats. Canadian Journal of Physiology and Pharmacology . 2009

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