喉癌主癌灶手术切缘的临床特点分析

Analysis of clinical features of surgical margin of the main site of carcinoma of larynx

目的探讨研究喉癌主癌灶手术的安全切缘在临床上的特点。方法回顾性分析2007年6月—2011年3月已经确诊喉癌的患者100例,随机分成A、B两组,A组为观察组50例,主要采取手术切缘后,然后采取镜下观察分析;B组为观察组50例,主要采取手术切缘后,然后采取肉眼观察分析,将结果进行临床特点分析比较。结果早期的喉癌患者和晚期的喉癌患者的阳性切缘例数,差异无统计学意义(P>0.05);晚期的阳性切缘发生次数高于早期的阳性切缘发生次数,差异有统计学意义(P<0.05)。声门上区[SG]2、3和5、10mm;跨声门型[TG]2、3mm和5、10mm的切缘对比,差异有统计学意义(P<0.05)。SG、G、TG、IG的2mm和3mm,5mm和10mm对,差异无统计学意义(P>0.05)。肉眼阳性切缘观察39个,镜下阳性切缘观察43,两者差异无统计学意义(P>0.05)。结论依据原发不同部位、不同分期和不同范围选取适合的切线,就可以有效地减少阳性切缘的发生。

Objective Explore and analyzed the clinical characteristics of laryngeal main foci surgery safe cutting edge.Methods Retrospective analyzed 100 cases diagnosed with laryngeal cancer from June 2007 to March 2011,randomly divided into two groups（A,B）,50 cases of group A in observation group,group B for observation group in 50 cases,analyzed and compared the results of clinical features.Results The early laryngeal cancer patients and the late with positive margins had no significant difference,（P〉 0.05）;late occurrence of positive margins was higher than early occurrence,the differences was statistically significant（P〈0.05）.Conclusion Basis for primary different parts,different stages and different range for selecting the suitable tangent,can effective reduced the occurrence of positive margins.