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黄芪多糖对白血病细胞MICA基因和蛋白表达水平及NK细胞杀伤敏感性的影响 被引量:5

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摘要 黄芪多糖(Astragalu spolysaccharide)是中药黄芪中最具免疫活性的成分,具有抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡的抗肿瘤特性n剖,但其作用机制尚不明确。我们通过观察黄芪多糖处理前后白血病细胞系HL-60、K562表面NKG2D(natural—killergroup2,memberD)配体MHC-I类链相关分子A(MICA)的表达及其对NK细胞的杀伤敏感性的影响,探讨黄芪多糖抗肿瘤作用的机制,为黄芪多糖联合NK细胞治疗白血病提供实验依据。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2012年第9期765-767,共3页 Chinese Journal of Hematology
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参考文献10

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二级参考文献20

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