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抗转化生长因子β诱导蛋白单克隆抗体的制备 被引量：1

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摘要 转化生长因子β诱导蛋白（transforming growthfactor-β-induced protein,TGFBIp）是一个多功能细胞外基质分子,在细胞黏附、迁移、增殖、分化中起十分重要作用[1,2]。近期Kim HJ等[3]及Rowley JW等[4]研究显示，TGFBIp可作为一种血小板来源蛋白，在血小板活化、促进血栓形成中发挥重要作用。因此，制备抗TGFBIp单克隆抗体将更好地理解血小板活化及血栓形成，为发展新的抗血栓治疗提供有价值的手段。1材料与方法1．1材料与动物1．1．
作者 李宗波 王玉亮
机构地区 天津市津南区咸水沽医院 天津市第一中心医院卫生部危重病急救医学重点实验室
出处 《生物医学工程与临床》 CAS 2012年第5期486-488,共3页 Biomedical Engineering and Clinical Medicine
基金 国家临床重点专科建设项目 卫生部危重病急救医学重点实验室建设项目
关键词 转化生长因子Β 单克隆抗体 诱导蛋白 制备 血小板活化 PROTEIN 细胞外基质分子 血栓形成
分类号 R363 [医药卫生—病理学]
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参考文献11

  • 1Runager K, Enghild JJ, Klintworth GK. Focus on molecules: Tra- nsforming growth factor beta induced protein (TGFBIp)[J]. Exp Eye Res, 2008, 87(4): 298-299.
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  • 3Kim HJ, Kim PK, Bae SM, et al. Transforming growth factor-bet- a-induced proteinfI'GFBIp/beta ig-h3) activates platelets and promotes thrombogenesis[J]. Blood, 2009, 114(25): 5206-5215.
  • 4Rowley JW, Weyrich AS, Campbell RA. TGFBIp: more than me- ets the eye[J]? Blood, 2009, 114(25): 5113-5114.
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  • 10阎欢,张珩,王玉亮.抗蛋白S单克隆抗体的制备[J].哈尔滨医科大学学报,2009,43(5):519-520. 被引量：1

二级参考文献27

  • 1杜雪梅,唐丽,柳晓兰,陈勇,高建恩,贺福初,孙启鸿.抗人LSECtin单克隆抗体的制备与初步鉴定[J].细胞与分子免疫学杂志,2006,22(4):517-520. 被引量：5
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生物医学工程与临床
2012年 第5期

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