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多西他赛联合希罗达治疗三阴性乳腺癌的临床观察 被引量:4

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摘要 目的探讨多西他赛联合希罗达治疗三阴性乳腺癌的临床疗效。方法对我院自2009年12月至2011年6月期间共收治26例三阴性乳腺癌女性患者采用多西他赛联合希罗达实施治疗,并评价其临床疗效与毒副反应。结果多西他赛联合希罗达化疗对单淋巴结阳性的有效率为73.3%,对多淋巴结阳性的有效率为45.5%,两者相比差异显著(P<0.05),具有统计学意义,年龄>45岁与≤45岁者的有效率分别为70.6%和44.4%,两者比较差异显著(P<0.05),具有统计学意义。结论三阴性乳腺癌对多西他赛与希罗达的敏感性及转归与患者年龄及肿瘤的淋巴结阳性个数密切相关,患者年龄愈小、淋巴结阳性个数愈多,其预后愈差。
作者 李豪
出处 《中国医药指南》 2012年第23期156-157,共2页 Guide of China Medicine
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