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R-GDP方案一线治疗弥漫大B细胞淋巴瘤的疗效分析

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摘要 目的回顾性研究美罗华(R)联合吉西他滨(GEM)、顺铂(DDP)、地塞米松(DXM)组成的R-GDP方案一线治疗弥漫大B细胞淋巴瘤(DLBCL)的疗效和毒副反应。方法 2009年1月至2011年7月我科收治的52例初治DLBCL患者,给予R-GDP方案化疗,2ld为l周期。4个周期后评价疗效,并随访疾病进展情况。结果 52例患者,CR28例,PR16例,SD2例,PD6例,总体缓解率84.62%。可随访评价的50例患者中位TTP为20.00个月(95%CI:10.55~29.45个月)。毒副反应主要为骨髓抑制和轻中度的消化道反应。结论 R-GDP方案一线治疗弥漫大B细胞淋巴瘤的疗效好,不良反应轻。
出处 《中国医药指南》 2012年第23期170-172,共3页 Guide of China Medicine
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