系统性红斑狼疮的神经系统表现

NFUROLOGIC MANIFESTATIONS IN PATIENTS WITH SLE

本文报告了166例系统性红斑狼疮(SLE)病人中有神经系统损害的50例资料。其表现依次有精神异常、癫痫发作、头痛、视神经损害、颅神经麻痹、偏瘫、周围神经病,肌病,假性延髓麻痹、震颤、截瘫及尿失禁。侵犯神经系统涉及中枢至周围神经直至肌肉各个部位。

The authors reported 50 cases of neurologic manifestations in 166 patients with systemic lupus erythematoses (SLE), which showed orderly as mental disorders, seizure, headache, optic nerve lesions, cranial nerve palsy, hemiplegia, peripheral neuropathy, myopathy, pseudobulbar palsy, tremor, paraplegia and urinary incontinence. The lesions involved central nerve system, peripheral nerve system and muscular system, one patient might show lesions in more than one part of his body. To diagnose SLE was very difficulty in the early stage of this disease when there were manifestations of nerve system lesion only. When one young woman who has manifestations of nerve lesions was excluded to be ill with other diseases, the possibility of SLE may be considered. The authors reviewed the literature and the pathogencsis of these eomlications and tried to inquire into it further