宫颈环形电切术与传统冷刀锥切术治疗上皮内瘤变临床对比研究

Cervical loop electrosurgical excision procedure with the traditional cold-knife conization in the treatment of intraepithelial neoplasia clinical study on the effect

目的探讨宫颈环形电切术(LEEP)与宫颈冷刀锥切术(CKC)治疗宫颈上皮内瘤病(CIN)的临床效果。方法 56例宫颈上皮内瘤变患者,按入院先后分为LEEP组和CKC组各28例,分别采用宫颈环形电切术和宫颈冷刀锥切术治疗,比较2组手术及并发症发生情况。结果 LEEP组术后痊愈率96.43%,CKC组92.86%,2组比较差异无统计学意义(P>0.05)。手术时间、术中出血量、术后切口愈合时间LEEP组明显优于CKC组,2组比较差异有统计学意义(P<0.05)。结论 LEEP术治疗CIN操作简单,并发症少,手术时间和切口愈合时间及术中出血量均优于CKC术,值得推广应用。

Objective To investigate the clinical effect of the excision （CKC）fibromatosis in the treatment of cervical intraepithelial （CIN）, cervical loop eleetrosurgieal excision procedure （LEEP）and cervical cold knife cone. Methods patients admitted to hospital in July 2010 N March 2012 cervical intraepithelial neoplasia 56 cases, has hospitalized patients were divided into the LEEP group and the CKC group, cervical loop electrosurgical excision procedure and cervical cold knife cone resection, and compare the two groups of patients with surgery and complications occur. Results of LEEP group was cure rate of 96.43% ,92.86% of the CKC, group, the difference was not statistically significant（P 〉 O. 05）. Operative time, blood loss, postoperative wound healing time LEEP group was significantly better than the CKC group, the difference was statistically significant（P 〈 0.05 ）. Conclusion LEEP treatment of CIN surgical operation is simple, complications, operative time and wound healing time and bleeding volume than CKC operation, should be widely applied.