30例输血不良反应的原因分析

An analysis on the causes of adverse reactions associated with blood transfusion

目的通过对我院发生的输血不良反应进行调查分析，以寻找减少不良反应发生的有效措施。方法通过查阅我院2007年1月至2011年6月期间3455例输血患者的病历和输血反应回报单，对输血不良反应情况进行统计分析。结果本次调查输血病人3455例，输血不良反应有30例（发生率为0．87％），其中以悬浮红细胞、新鲜冰冻血浆和机采血小板等三种血液成分引起输血反应发生率最高。30例输血不良反应均为非溶性输血反应，包括有发热反应19例、过敏反应9例及全身不适2例，其中1h内发生的有23例，2h内发生的有5例，3h内发生的有2例。结论坚持科学合理的用血原则，输血前有针对性采取适当措施可有效降低输血不良反应率。

Objective To seek an effective method for reducing the occurrence of adverse reac- tions associated with blood transfusion by analyzing those adverse reactions in our hospital. Methods The medical history and the report sheets for transfusion reactions in 3455 patients who had received blood transfusion during the period of January 2007 to June 2011 were reviewed. The adverse reactions were statistically analyzed. Results 30 of all of the 3455 patients （ 0.87% ） developed adverse reactions associated with transfusion. The most frequent adverse reactions were caused by suspended red blood cells, fresh frozen plasma and platelets. They were non soluble transfusion reactions, including 19 cases of fever, 9 cases of hypersensitivity, and 2 cases of general malaise. 23 patients occured reactions within 1 h, 5 within 2 h, and 2 with 3 h, Conclusions We should stick to the principle of rational blood transfusion. Proper measures taken before transfusion can effectively reduce the rate of adverse reactions associated with blood transfusion.