血清CA125、CEA水平与宫颈癌相关性分析

Association of serum carcinoembryonic antigen and carbohydrate antigen 125 with cervi- cal cancer

目的分析研究血清CA125（糖链抗原125）、CEA（癌胚抗原）水平与宫颈癌的相关性。方法将我院从2007年2月至2011年3月收治的100例宫颈癌病患设为实验组，进行血清CA125、CEA水平检测，并与宫颈癌分期相分析，将同期收治的60例非宫颈癌病患设为对照组，对比两组血清CA125、CEA水平。结果实验组血清CA125、CEA水平均高于对照组，除Ⅰ期宫颈癌数据外，差异有统计学意义（p〈0．05）；血清CA125与宫颈癌分期的相关性高于血清CEA，差异有统计学意义（P〈0．05）。结论血清CA125、CEA水平与宫颈癌有一定相关性，检测简单方便，且血清CA125比血清CEA更具诊断价值。

Objective To analyze the association of serum carcinoembryonic antigen （CEA） and carbohydrate antigen 125 （CA125） with cervical cancer. Methods 100 patients with cervical cancer who had been treated in our hospital during the period of February 2007 to March 2011 were enrolled into a study group. Serum levels of CEA and CA125 were detected and their assoication with cervical cancer was analyzed; and the levels of these markers were compared with those from 60 non-cervical cancer patients （ control group ）. Results Serum levels of CEA and CA125 were higher in the study group than in the control group, with a significant difference between 2 groups （ P〈 0.05 ） except for stage I cervical cancer. The correlation between CA125 and stages of cervical cancer was greater than that between CEA and cervical cancer （ P〈 0.05 ）. Conclusions Serum levels of CEA and CA125 are associated with cervical cancer at some degree. CA125 has more diagnostic values than CEA.