自体颅骨瓣骨基质明胶原位植入颅骨成形术

CRANIOPLASTY WITH AUTOLOGOUS CRANIAL BONE MATRIX GELATIN

本文报告使用一种新的生物材料——自体颅骨BMG原位植入修补颅骨缺损的3例病人初步观察。3例病人都因颅脑损伤而开颅,颅骨经钻洞和锯缝后,制备成BMG,在适当的时间原位植入。随访时间最长13月,最短2月。随访结果:植入3～5月内,成骨活跃;9～13月骨化区停止扩大,但密度加深,说明本材料是有生物活性的,能诱导成骨,又能作为成骨的支架,是一项颇有前途的修补颅骨缺损的材料。

This is a preliminary report of three cases of cranicplasties by implantations in situ with autologous bone matrix gelatin flaps. The excised cranial flaps obtained from cratliotomies were prepared by drillings and sa-w cuts, and then by chemical means for BMG.The follow-up perieds varied from 2 to 13 months. Rcentgenographi-cally.they showed active osteogencsis within 3 months after implantation and conti- nued for 8 months. Then it stopped extending.Clinical experiences proved the material is bio-active. It could induce osteogenesis. The brilliant prospect of cranioplas-ty encourages further detailed studies.