尾型同源盒基因与肿瘤

CDX gene and tumor

尾型同源盒基因（CDX）家族主要包括CDX1、CDX2、CDX4，是同源盒基因（HOX）Para-HOX家族中的一员，作为转录调节因子在胚胎发育造血系统形成、肠上皮组织发育等过程中起了重要的作用。CDX异常表达常与肿瘤发生密切相关。研究CDX与肿瘤发生的关系，对肿瘤诊断、治疗等有重要意义。

The caudal-type homeobox gene is a member of homeobox gene--Para-HOX family, inclu- ding CDX1, CDX2 and CDX4. As a transcriptional factor, CDX plays an important role in embryo development, hematopoietic system formation, intestinal epithelium tissue development and so forth. The abnormal expression of CDX is usually closely related with tumorigenesis. Researching the relationship between CDX and tumors will contribute to tumor diagnosis and treatment.