全身骨显像与CT对儿童神经母细胞瘤骨转移的诊断价值

Comparison of whole body bone scan and CT in diagnosing bone metastases of neuroblastoma in children

目的:比较全身骨显像及CT对儿童神经母细胞瘤骨转移的诊断价值。方法:选取经病理、影像学检查或临床随访等证实合并有骨转移的56例神经母细胞瘤患儿,比较全身骨显像及CT诊断神经母细胞瘤骨转移的阳性率。结果:全身骨显像与CT诊断神经母细胞瘤患儿骨转移一致性差(kappa=0.231,P=0.007);全身骨显像与CT诊断骨转移阳性率分别为91.1%和57.1%。结论:两种方法均可诊断神经母细胞瘤骨转移,但全身骨显像的诊断效能优于CT。

Aim ：To compare the value of whole body bone scan（WBS） and CT in diagnosing bone metastases of neuroblastoma in children. Methods：A total, of 56 children who were formerly confirmed as bone metastasis by pathology, video-imaging or clinical follow-up, performed WBS and CT,respectively. The positive rate of the two methods in diagno- sing bone metastases of neuroblastoma was compared. Results ： Consistency of WBS and CT in diagnosing bone metastasis of neuroblastoma was poor（kappa =0. 231 ,P =0. 007） ,and the positive rate was 91. 1% and 57. 1% ,respectively. Conclusion ：Bone metastasis of neuroblastoma can be diagnosed by both WBS and CT; diagnostic efficiency of WBS is higher than CT.