抗血栓新药蕲蛇酶

A NEW ANTITHROMBOTIC AGENT ACUTOBIN

综述了蕲蛇酶中药物性质、药理作用、药代动力学、毒理作用以及临床应用。蕲蛇酶具有降低血中纤维蛋白原浓度、抑制血小板聚集、预防血栓形成和溶解血栓作用 ,且毒性较低 ;临床试验表明 ,对急性脑梗塞总有效率分别为 92 .2 %和 94.2 % ,且不良反应少 ,是一种安全、有效的新药。

Acutobin has the action of lowering blood fibrinogen level,inhibiting platelet aggregation,preventing thrombosis and dissolving thrombus.In this paper, the pharmaceutical properties,pharmacological action, pharmacokinetics and clinical uses of Acutobin were reviewed.