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抗肝病毒药物的药物代谢动力学研究进展 被引量:4

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摘要 目的综述抗肝病毒药物药物代谢动力学研究发展。方法参阅近十年国内外文献,将抗肝病毒药物按来源分类分为化学药物、生物制剂以及传统中药,分析、总结和归纳了各类抗肝病毒药物的药物代谢动力学研究成果。结果以抗乙肝病毒(HBV)治疗药物为例,揭示出各类药物在肝炎患者体内的吸收、分布、代谢和排泄(ADME)过程的特征。结论在概述抗肝病毒药物的药物代谢动力学特征基础上对未来抗肝病毒药物的发展趋势进行展望,为今后抗肝病毒药物的研究与应用提供必要的参考。
作者 徐聪 曾苏
出处 《中国药学杂志》 CAS CSCD 北大核心 2012年第18期1430-1433,共4页 Chinese Pharmaceutical Journal
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