38例胃肠间质瘤临床诊治分析

A clinical diagnosis and treatment of 38 patients with gastrointestinal stromal tumors

目的探讨胃肠间质瘤的临床特点及诊疗方法。方法回顾性分析我院自2003年5月至2010年5月治疗的38例胃肠间质瘤的临床资料及随诊结果。结果手术切除率94.7%,所有病例随访1-5年,复发24例,带瘤生存10例,无瘤生存18例,死亡3例。本组病例23例术后未口服格列卫治疗,复发率86.96(20/23)%;15例口服格列卫治疗,复发率26.67%(4/15)。结论胃肠间质瘤治疗以外科手术完整切除为主,术后口服格列卫治疗能明显提高生存率。

Objective To probe on characteristics and methods of diagnosis and treatment on gastrointestinal stromal tumors. Methods Retrospectively reviewed 38 patients with gastrointestinal stromal tumor＇s clinical information and follow-up results from 2003 May to 2010 May. Results Surgical resection rate was 94.7%, follow-up 1-5 year,relapse 17 cases,survival 10 cases,disease-free survival 18 cases,deaths 3 cases. 23 cases after operation did not receive Gleevec therapy,relapse rate was 86.96%.15 cases had Gleevec therapy.Recurrence rate was 26.67 %. Conclusions Gastrointestinal stromal tumors surgical complete excise and postoperative oral administration of Gleevec therapy can significantly improve survival rates.