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右旋美托咪啶在悬雍垂腭咽成形术经鼻清醒气管插管中的应用 被引量:4

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摘要 目的探讨右旋美托咪啶(Dex)用于悬雍垂腭咽成形术清醒气管插管的可行性。方法择期行悬雍垂腭咽成形术患者40例,随机分为两组(n=20):咪达唑仑(Ⅰ组)和右旋美托咪啶(Ⅱ组)。记录两组麻醉前(T1),气管插管即刻(T2),气管插管后3min(T3)HR、MAP、和SpO2,结果两组患者均插管成功。但Ⅱ组患者类似自然睡眠,各时点MAP、HR、SpO2无明显变化,P>0.05无统计学意义。Ⅰ组T2时MAP、HR、SpO2有明显变化,P<0.05有统计学意义。两组配合清醒插管合作度有差异。结论右旋美托咪啶+表面局部麻醉可为悬雍垂腭咽成形术的患者清醒气管插管提供安全有效的镇静。
机构地区 南昌市第一医院
出处 《江西医药》 CAS 2012年第7期621-622,637,共2页 Jiangxi Medical Journal
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参考文献3

  • 1庄心良;曾因明;陈伯銮.现代麻醉学[M]北京:人民卫生出版社,20031185.
  • 2张燕,郑利民.右美托咪啶的药理作用及临床应用进展[J].国际麻醉学与复苏杂志,2007,28(6):544-547. 被引量:224
  • 3CJ Tsai,KS Chu,TI Chen. A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreoptic nasotracheal intubation[J].Anaesthesia,2010.254.

二级参考文献20

  • 1Sturaitis MK, Braverman B, Tuman KJ. Effect of dexmedetomidine on somatosensory evoked potentials in patients during craniotomy. Anesthesiology, 2003 (abstr) , 99 :A291.
  • 2Paris A, Mantz J, Tonner PH, et al. The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the [ alpha]2A - adrenoceptor subtype. Anesthesia & Analgesia, 2006, 102:456-461.
  • 3Dahmani S, Rouelle D, Gressens P, et al. Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions. Anesthesiology, 2005, 103:969- 977.
  • 4Taniguehi T, Kidani Y, Kanakura H, et al. Effects of dexmedetomidine on mortality rate and inflammatory, responses to endotoxin - induced shock in rats. Critical Care Medicine, 2004, 32:1322-1326.
  • 5Davies MF, Haimor F, Lighthall G, et al. Dexmedetomidine fails to cause hyperalgesia after cessation of chronic administration. Anesthesia & Analgesia, 2003, 96 : 195-200.
  • 6El - Kerdawy H, Gouda N, Kamal H. Dexmedetomidine as anaesthetic adjunct for patients undergoing off - pump coronary artery bypass grafting. Egyptian Journal of Anaesthesia, 2004, 20:29-34.
  • 7Jooste EH, Ohkawa S, Sun LS, et al. Fiberoptie intubation with dexmedetomidine in two children with spinal cord impingements. Anesthesia & Analgesia, 2005, 101 :1248.
  • 8Ramsay MA, Luterman DL . Dexmedetomidine as a total intravenous anesthetic agent. Anesthesiology, 2004, 101:787-790.
  • 9Bekker AY, John B, Mark G, et al. Dexmedetomidine for awake carotid endarterectomy: efficacy, hemodynamic profile, and side effects. Survey of Anesthesiology, 2005, 49:248-249.
  • 10McCutcheon CA, Orme RM, Scott DA, et al. Hemodynamic control during carotid endarterectomy performed under regional anesthesia. Anesthesia & Analgesia, 2006, 102:668-675.

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